Human IkB-alpha PharmaGenie ELISA Kit (SBRS0712)

This in vitro research-use-only colorimetric ELISA kit from Assay Genie enables quantitative measurement of inhibitor of NF-kB alpha (IkB-alpha) in human samples, supporting research into NF-kB pathway regulation, inflammatory signaling, and cellular stress responses. The kit includes pre-coated plates, standards, and reagents configured for 96 assays, enabling medium-throughput studies in academic and pharmaceutical laboratories.

IkB-alpha functions as the principal cytoplasmic repressor of NF-kB transcription factors; its phosphorylation triggers proteasomal degradation, releasing NF-kB to enter the nucleus and drive pro-inflammatory gene expression. Scientists studying cytokine signaling, immune cell activation, oncogenic transformation, or drug mechanism-of-action experiments routinely monitor IkB-alpha as a downstream indicator of pathway activity. The assay accepts cell culture supernatants, plasma, and serum specimens.

Provided as a complete ELISA kit with ready-to-use reagents and a streamlined workflow, the format supports reproducible quantification across multiple sample types from a single standard curve.