Human IgG4/Immunoglobulin G4 ELISA Kit

Differentiating the four human IgG subclasses clarifies immunological status, since IgG4 normally represents only about 3–5% of total IgG and exhibits unusual functional behaviors such as dynamic Fab-arm exchange and limited classical complement activation. Quantitative measurement of IgG4 supports research into IgG4-related disease, allergic and parasitic immune responses, autoimmune pancreatitis, and pharmacokinetic monitoring of therapeutic IgG4 monoclonal antibodies including checkpoint inhibitors used in oncology.

This 96-assay enzyme-linked immunosorbent kit from Assay Genie is configured for quantitative work with human blood-derived specimens and delivers a chromogenic endpoint read-out compatible with standard microplate readers. Each kit contains the reagents required for in vitro research workflows; components should be refrigerated between uses to preserve activity. The 96-assay format accommodates patient cohort studies and longitudinal sampling designs where subclass-specific reproducibility across wells is required.