Human ICOS ligand (ICOSLG) ELISA Kit

Assay Genie offers a sandwich-format ELISA kit for the quantitative detection of human ICOS ligand (ICOSLG), a membrane protein that acts as a ligand for the T-cell-specific cell surface receptor ICOS. The assay provides a costimulatory signal for T-cell proliferation and cytokine secretion, and also induces B-cell proliferation and differentiation into plasma cells, with the protein implicated in local tissue responses to inflammatory conditions and in modulating secondary immune responses by co-stimulating memory T-cell function. The colorimetric assay is intended for research use only and supports studies of immune modulation, inflammation, autoimmune disease, and cancer, where ICOSLG is highlighted as a potential therapeutic target and diagnostic biomarker.

Validated for use with human serum, plasma, tissue homogenates, cell culture supernatants, and other biological fluids, the kit is specific for natural and recombinant human ICOS ligand. Linearity and recovery data are provided across serum, EDTA plasma, and heparin plasma sample matrices.