Human ICMT (Protein-S-isoprenylcysteine O-methyltransferase) ELISA KIT (HUFI05134)

Post-translational modification by isoprenylation controls the membrane association and signaling activity of CAAX motif proteins, including the Ras family of oncogenic GTPases. ICMT (Protein-S-isoprenylcysteine O-methyltransferase) catalyzes the final carboxyl-methylation step in this pathway at the endoplasmic reticulum membrane.

Assay Genie's immunoassay kit for human ICMT delivers quantitative measurement of the enzyme across research specimens. Each pack contains pre-coated microplate wells, matched detection antibodies, calibration standards, wash buffers, and substrate to support one complete 96 Assays plate run with a spectrophotometric endpoint. Investigators studying prenylation pathway biology, KRAS-driven tumor models, or membrane-associated enzyme regulation can integrate this plate-based readout into existing cell lysate and tissue homogenate workflows.

Components are intended for laboratory research use only and should be stored refrigerated between runs to maintain antibody binding activity through the stated shelf life. Sufficient reagents are supplied in a single box to process one microplate per kit.