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Human ICA1 (Islet cell autoantigen 1) ELISA Kit (HUFI05128)
  • Human ICA1 (Islet cell autoantigen 1) ELISA Kit (HUFI05128)
Assay Genie

Human ICA1 (Islet cell autoantigen 1) ELISA Kit (HUFI05128)

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HUFI05128

Price on request

Description

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Designed to support research into the autoimmune mechanisms underlying Type 1 diabetes, the Assay Genie Human ICA1 ELISA Kit provides a quantitative immunoassay for Islet Cell Autoantigen 1, also known as ICA69. This 69 kDa protein is a well-characterized target of humoral autoimmunity in insulin-dependent diabetes, and circulating ICA1 autoantibodies are investigated as serological indicators of beta-cell damage, disease progression, and elevated risk in first-degree relatives of affected individuals.

Each kit is configured for 96 individual determinations and follows a standard ELISA workflow in which pre-coated microplate wells are incubated with calibrators and research samples, washed, exposed to a conjugated detection reagent, developed with substrate, and quantified by absorbance reading on a standard microplate reader. The assay is intended for research use only in laboratory settings and is not approved for diagnostic procedures.

Researchers studying islet autoantibody profiles, prediabetic immune activation, islet transplantation outcomes, or the development of predictive biomarkers for Type 1 diabetes will find this kit a practical tool for cohort screening and translational endocrinology studies. Compatible sample matrices include those routinely collected in clinical diabetes research programs.