Human IARS2 ELISA Kit (HUFI03851)

Mitochondrial isoleucyl-tRNA synthetase 2 (IARS2) can be quantitatively measured in human research samples using this ELISA assay, supplied by Assay Genie in a 96 Assays format. IARS2 is a nuclear-encoded enzyme that catalyzes the attachment of isoleucine to its cognate mitochondrial tRNA, supporting translation of mitochondrially-encoded protein subunits required for oxidative phosphorylation. The kit is intended for research use only and supports investigations into mitochondrial aminoacyl-tRNA synthetase function, mitochondrial translation disorders, and conditions associated with IARS2 dysfunction, including reported links to progressive leukoencephalopathy with hearing loss and early-onset mitochondrial disease phenotypes in published case studies.

Researchers studying aminoacyl-tRNA synthetase biology, mitochondrial protein synthesis, or IARS2-related disease models will find this assay useful for characterizing target protein levels in their experimental samples. The plate-based measurement workflow integrates into standard ELISA instrumentation, providing a readout that supports both relative and absolute quantification of IARS2 in laboratory studies. All reagents required to carry out the measurement protocol are included in the supplied 96 Assays packaging.