Human Huntingtin (HTT) ELISA Kit

From Assay Genie, this Sandwich ELISA Kit is designed for the precise measurement of human Huntingtin (HTT) in serum, plasma, and cell culture supernatants. The kit uses a colorimetric detection method and is intended for research use only.

Reported performance figures include a detection range of 15.6-1000pg/mL, a sensitivity of 4.2pg/mL, an intra-assay CV of 4.7%, and an inter-assay CV of 7.5%. Specificity is reported for natural and recombinant human Huntingtin (UniProt P42858), and listed synonyms include Huntington disease protein, HD protein, HD, and IT15.

Huntingtin plays roles in intracellular trafficking, transcriptional regulation, and cell survival, and mutations in the gene are implicated in Huntington's disease, a neurodegenerative disorder characterized by progressive motor and cognitive impairment. The kit supports research in neurosciences, with the protein's reported subcellular localisation in the cytoplasm and nucleus.