Human Hornerin (HRNR) ELISA Kit

From Assay Genie, this Sandwich ELISA kit is designed for the precise measurement of hornerin levels in human samples. It reacts with human hornerin (HRNR), a protein described as playing a vital role in skin barrier function and epidermal differentiation, and dysregulation of which has been linked to various skin disorders and inflammatory conditions. The assay is intended for use with serum and plasma, with additional compatibility reported for tissue homogenates, cell culture supernatants, and other biological fluids.

Performance characteristics include a detection range of 0.156-10 ng/mL, sensitivity of 0.098 ng/mL, an intra-assay CV of 5.8%, and an inter-assay CV of 8.9%. Detection is colorimetric, and the kit shows specificity for natural and recombinant human hornerin. Hornerin (synonym S100A18; UniProt Q86YZ3) is described as a component of the epidermal cornified cell envelopes, may play a role in cornification, and belongs to the S100-fused protein family.

For research use only.