Human Holliday junction recognition protein (HJURP) ELISA Kit

Assay Genie's Human Holliday junction recognition protein (HJURP) ELISA Kit is a sandwich-format immunoassay designed for the quantitative detection of HJURP in human research samples. The kit is intended for research use only and offers a tool for studying this centromeric protein, which acts as a specific chaperone for CENPA, supports the incorporation and maintenance of histone H3-like variant CENPA at centromeres, and directly binds Holliday junctions, making it central to DNA replication, repair and genomic stability.

Validated sample types include serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, with reactivity confirmed for human samples. The assay has a detection range of 0.625-40ng/mL and a sensitivity of 0.314ng/mL. Specificity covers natural and recombinant human Holliday junction recognition protein, and the target is also known by the synonyms 14-3-3-associated AKT substrate, Fetal liver-expressing gene 1 protein, Up-regulated in lung cancer 9, FAKTS, FLEG1, and URLC9 (UniProt: Q8NCD3; reported molecular weight 74,372 Da).