Human HLA class II histocompatibility antigen gamma chain (CD74) ELISA Kit

Designed by Assay Genie for the quantitative detection of human HLA class II histocompatibility antigen gamma chain (CD74), this Sandwich ELISA kit uses a colorimetric detection method and is validated for use with human serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay recognises natural and recombinant human CD74 and is intended for research use only, including applications within the cancer research area.

Performance characteristics include a detection range of 0.625-40 ng/mL and a sensitivity of 0.156 ng/mL, supporting accurate and reproducible measurement of CD74 levels. Precision is reported as an intra-assay CV of 5.8% and an inter-assay CV of 9.3%, with linearity and recovery data supplied across serum and plasma matrices.

CD74, also known as the invariant chain or gamma chain of the major histocompatibility complex class II, plays a crucial role in presenting antigens to T cells and in modulating immune responses. Its dysregulation has been associated with autoimmune diseases, cancer, and inflammatory conditions, making this kit a useful tool for biomarker studies and therapeutic target research.