Human HLA class II histocompatibility antigen, DRB1-15 beta chain (HLA-DRB1-15) ELISA Kit

This sandwich ELISA kit from Assay Genie is designed for the measurement of human HLA class II histocompatibility antigen, DRB1-15 beta chain (HLA-DRB1-15) in human samples, using a colorimetric detection method. The assay is validated for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.

HLA-DRB1*15 plays a critical role in antigen presentation and immune response regulation. Dysregulation of HLA-DRB1*15 has been linked to various autoimmune diseases, including rheumatoid arthritis and multiple sclerosis, highlighting its importance as a biomarker for research into these conditions. The kit delivers a detection range of 0.78-50 ng/mL with a sensitivity of 0.34 ng/mL, and shows specificity for natural and recombinant human HLA class II histocompatibility antigen, DRB1-15 beta chain.

The target is also known by the synonyms DW2.2/DR2.2, MHC class II antigen DRB1*15, and HLA-DRB2, and is associated with UniProt entry P01911. This product is for research use only.