Human HLA class II histocompatibility antigen, DRB1-11 beta chain (HLA-DRB1) ELISA Kit

A Sandwich ELISA developed by Assay Genie for the quantitative measurement of human HLA class II histocompatibility antigen, DRB1-11 beta chain (HLA-DRB1). The kit is intended for research use only and is described as a comprehensive tool for the precise measurement of HLA-DRB1 levels in human samples.

The assay has a detection range of 0.625-40ng/ml and a sensitivity of 0.322ng/mL, with reactivity specific to human samples. It is validated for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The kit shows specificity for natural and recombinant human HLA class II histocompatibility antigen, DRB1-9 beta chain, and is referenced under UniProt Q9TQE0. Synonyms listed for the target include MHC class II antigen DRB1*9 and DR-9.

HLA-DRB1 is described as a key component of the human immune system, playing a role in antigen presentation and immune response regulation. Variations in HLA-DRB1 expression are associated with autoimmune diseases, infectious diseases, and transplant rejection, making it a significant biomarker for studying immune-related conditions and developing therapeutic interventions.