Human Histone acetyltransferase KAT8 (KAT8) ELISA Kit

From Assay Genie, this ELISA Kit enables quantitative measurement of Histone acetyltransferase KAT8 (also known as MOF and MYST1) in human research samples. The kit reacts with serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.

KAT8 is a histone acetyltransferase that contributes to epigenetic regulation by acetylating histone H4 at lysine 16, with roles in chromatin remodeling and gene expression. Dysregulation of KAT8 has been associated with cancer, developmental disorders and other disease states, making it a target of interest in biomedical research. Manufacturer specifications report a detection range of 0.312-20ng/mL, sensitivity of 0.11ng/mL, intra-assay CV of 6.9% and inter-assay CV of 9.2%, with serum recovery averaging 102% (range 96-108%) and plasma recovery averaging 104% (range 98-110%).

Specificity covers natural and recombinant human Histone acetyltransferase KAT8 (UniProt Q9H7Z6), localised in the nucleus and on chromosomes. The product is intended for research use only; supplier data indicates storage at -20°C and shipping at +4°C.