Human Histatin-3 (HTN3) ELISA Kit

From Assay Genie, this Colorimetric Sandwich ELISA Kit is intended for the quantitative detection of Human Histatin-3 (HTN3) in human samples including serum, plasma, tissue homogenates, cell culture supernatants, and other biological fluids. The kit is for research use only.

Performance characteristics stated by the manufacturer include a detection range of 12.5–800 ng/mL, a sensitivity of 8 ng/mL, an Intra-assay CV of 4.3% and an Inter-assay CV of 7.5%. The assay detects natural and recombinant human Histatin-3, with alternative names including Basic histidine-rich protein, Histidine-rich protein 3, PB, Hst, and HIS2.

Histatin-3 is a secreted salivary peptide of the histatin/statherin family that contributes to the innate immune response in the oral cavity and exhibits antibacterial and antifungal activities. The derived His3-(20-43)-peptide (histatin-5) is particularly active against C. albicans and C. neoformans, and acts as an inhibitor of metalloproteinases MMP2 and MMP9. The protein is catalogued under UniProt P15516 and is associated with the Metabolism research area.