Human High Mobility Group Protein 1 (HMG1) ELISA Kit

HMGB1, also termed High Mobility Group Protein 1 (HMG1), is a highly conserved non-histone chromatin-binding protein that operates inside the nucleus as an architectural transcription factor and, once released into the extracellular space, behaves as a prototypical damage-associated molecular pattern driving inflammation, sepsis, sterile injury responses, autoimmunity, and tumour progression. The Assay Genie human HMG1 immunoassay is supplied as a complete research-use-only kit with pre-coated microplate strips, lyophilised standards, biotinylated detection reagent, streptavidin-HRP conjugate, wash buffer, substrate solution, and stop reagent, configured for two-antibody capture of the alarmin from human blood-derived samples including serum, heparin plasma, and EDTA plasma in a single microplate workflow with chromogenic readout. Reagents should be kept refrigerated between uses to preserve antibody binding activity and standard integrity, and the assay is intended strictly for in vitro research applications such as biomarker discovery, inflammatory-disease mechanism studies, and patient-cohort profiling where HMGB1 concentrations are reported against a standard curve. Each kit provides materials for 96 determinations, and its format is compatible with routine plate-reader instrumentation used in immunology, cell biology, and translational-research laboratories.