Human HIC2 (Hypermethylated in cancer 2 protein) ELISA KIT (HUFI05140)

This quantitative immunoassay from Assay Genie measures HIC2 (Hypermethylated in cancer 2 protein) levels in human-derived research specimens. HIC2 is a BTB/POZ domain zinc finger transcriptional repressor located on chromosome 22q11.21, structurally related to the HIC1 tumor suppressor. Aberrant hypermethylation of HIC family genes has been documented across multiple cancer types, making quantitative protein measurement valuable for oncology and epigenetics research.

The microplate-based kit provides all reagents needed for the standard curve and sample runs, with absorbance-based readout compatible with standard laboratory plate readers. Each kit is configured for 96 Assays and includes a pre-coated plate, detection antibody, standards, and buffers. The assay specifically detects human HIC2 protein and is intended for research use only, supporting studies of DNA methylation patterns, transcriptional regulation, and tumor biology in cell biology workflows.

Storage at refrigerated temperatures is recommended for unopened components, with working solutions prepared according to the included protocol. Researchers investigating hypermethylation in cancer, POZ domain transcription factors, or related signaling pathways can use this kit alongside nucleic acid-based methylation analyses to bridge genomic findings with protein-level expression in vitro.