Human HIBADH (3-hydroxyisobutyrate dehydrogenase, mitochondrial) ELISA KIT (HUFI05496)

Quantify mitochondrial 3-hydroxyisobutyrate dehydrogenase (HIBADH) with this research-use-only immunoassay kit from Assay Genie, supplied as a complete package sufficient for 96 individual assays.

HIBADH functions within the valine catabolism pathway inside the mitochondrial matrix, converting 3-hydroxyisobutyrate to methylmalonate semialdehyde as part of branched-chain amino acid breakdown. Altered enzyme activity and expression have been investigated in studies of metabolic liver disorders, breast cancer metabolic reprogramming, and rare inborn errors affecting branched-chain amino acid catabolism.

The kit provides laboratories with a dependable tool for biomarker discovery, mitochondrial enzyme profiling, and mechanistic studies in metabolic and oncology research. All reagents should be handled according to the enclosed protocol, with refrigerated storage recommended for unopened components and aliquoted frozen storage for reconstituted standards to preserve activity across multiple freeze-thaw cycles as limited by the product insert.