Human HHAT (Protein-cysteine N-palmitoyltransferase HHAT) ELISA KIT (HUFI05181)

The Assay Genie HHAT ELISA kit enables quantitative measurement of human Hedgehog acyltransferase, the endoplasmic reticulum-resident enzyme that palmitoylates the N-terminal cysteine of Hedgehog ligands, a lipidation step required for full signaling output of Sonic, Indian, and Desert Hedgehog. Investigators studying basal cell carcinoma, medulloblastoma, and pancreatic ductal adenocarcinoma use HHAT protein quantification to evaluate Hedgehog pathway activation and to screen candidate small-molecule inhibitors of this enzyme. The kit uses a human-specific antibody pair, and each microplate run yields quantitative data with applications in oncology, developmental biology, and signal transduction research, with reconstituted reagents stable when stored refrigerated at 4 °C.