Human Heparan Sulfate-2-O-Sulfotransferase 1 (HS2ST1) ELISA Kit

For researchers studying heparan sulfate biosynthesis, this Assay Genie ELISA kit enables quantitative measurement of Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1), the Golgi-resident enzyme that installs 2-O-sulfate groups onto uronic acid residues during chain modification. The colorimetric format supports investigations into how altered 2-O-sulfation patterns influence growth factor signaling, extracellular matrix organization, and tumor cell migration.

Configured for human samples, the assay accepts tissue homogenates and related biological preparations, enabling studies of HS2ST1 expression across cultured cell lines, primary tissues, and disease models where dysregulated sulfotransferase activity has been documented. Investigators probing HS2ST1 knockout phenotypes, heparan sulfate proteoglycan remodeling, or the contribution of 2-O-sulfation to FGFR and VEGF signaling can integrate this kit into existing workflows.

Each kit provides reagents sufficient for 96 assays, accommodating screening of experimental conditions, time-course experiments, and comparative panels of patient-derived samples. The components are intended for in vitro research use only and are not validated for diagnostic or therapeutic decision-making.