Human Hemojuvelin (HJV) ELISA Kit

Hemojuvelin is a GPI-anchored co-receptor for bone morphogenetic proteins (BMPs) that helps regulate human iron homeostasis by modulating hepatic hepcidin expression. Mutations in the HJV gene cause juvenile hemochromatosis, an autosomal recessive iron overload disorder associated with accelerated iron accumulation in the liver, heart, and endocrine organs. Researchers use the Assay Genie Human Hemojuvelin (HJV) ELISA Kit to quantify circulating and tissue-derived HJV in human serum or plasma, as well as tissue homogenates, cell lysates, and cell culture supernatants. The kit is supplied in a 96-assay format and is validated for in vitro research use only. Both membrane-bound and soluble HJV isoforms can be measured, supporting studies of BMP signaling in iron metabolism. Reconstituted reagents should be stored according to the product insert; protect from light to preserve assay performance across multiple freeze-thaw cycles.