Human Hematopoietic SH2 domain-containing protein (HSH2D) ELISA Kit

Assay Genie offers this Sandwich ELISA Kit for the quantitative measurement of human Hematopoietic SH2 domain-containing protein (HSH2D), also known by the synonyms ALX and HSH2. The assay is intended for use with human serum, plasma, tissue homogenates, cell culture supernates and other biological fluids and uses a colorimetric detection method. According to the manufacturer, the detection range is 0.156–10 ng/mL with a sensitivity of 0.078 ng/mL.

HSH2D is described as a modulator of the apoptotic response through its effect on mitochondrial stability and acts as an adapter protein in tyrosine kinase and CD28 signalling, influencing CD28-mediated activation of the RE/AP element of the interleukin-2 promoter. The protein localises to the cytoplasm and nucleus, interacts with FES and TNK2, and has a reported molecular weight of 32,704 Da. Its chromosomal location in humans is 19p13.11, and the UniProt accession is Q96JZ2.

Reactivity is limited to human samples, and the kit is supplied for research use only. A third-party listing indicates shipping at +4°C with storage recommended at −20°C.