Human Heat Shock Protein 90kDa Alpha A1 (HSP90aA1) ELISA Kit

Quantitative measurement of HSP90AA1, a 90 kDa stress-induced molecular chaperone central to protein folding and client-protein stabilization, supports research into cancer cell signaling, tumor microenvironment stress responses, and chaperone inhibitor screening. This Assay Genie kit is configured for 96 assays and accepts a diverse panel of human-derived inputs, including serum samples, plasma samples, tissue homogenates, cell lysates, and cell culture supernatants, enabling workflow flexibility across translational and basic research laboratories.

HSP90AA1 is frequently studied as a biomarker in oncology research, particularly in investigations of solid tumor progression, metastasis, and resistance to kinase inhibitor therapies. The chaperone stabilizes oncogenic client proteins such as HER2 and BCR-ABL, making it a recurring target in studies of cellular stress adaptation and pharmacological response. Researchers can profile HSP90AA1 expression across patient-derived specimens, xenograft tissue preparations, or treated cell lines to track chaperone dynamics under environmental or drug-induced challenge.

The kit is supplied in a 96 assays box format and intended for research use only. Standard immunoassay workflow applies, with components handled per the manufacturer's protocol and stored refrigerated to preserve antibody binding activity through the kit's shelf life. The assay supports laboratories studying heat shock biology, cancer biomarker discovery, chaperone pharmacology, and signal transduction pathways where HSP90 family activity contributes to disease phenotype.