Human HB-EGF PharmaGenie ELISA Kit (SBRS0662)

Heparin-Binding EGF-like Growth Factor (HB-EGF) is a mitogenic member of the EGF family that binds heparin and signals through EGFR and ErbB4 receptors, and is implicated in wound healing, cardiac development, smooth muscle proliferation, and tumor progression. This Assay Genie microplate kit enables researchers to measure HB-EGF in conditioned media from cultured cells as well as human plasma-derived and serum-derived specimens. HB-EGF functions as a potent mitogen for fibroblasts and contributes to angiogenesis and epithelial-to-mesenchymal transition in cancer biology, making it a target of interest in oncology, cardiovascular, and regenerative medicine studies. All reagents needed for the assay are included; refrigerate upon arrival and consult the package insert for storage of individual components. Intended for research use only.