Human HAMA (anti-mouse Ig Antibody) ELISA Kit

Quantifying Human Anti-Mouse Antibodies addresses a critical challenge in immunology and therapeutic antibody development. These endogenous antibodies, commonly referred to as HAMA, develop in patients following exposure to murine-derived monoclonal antibodies used in oncology, transplant medicine, and autoimmune therapy. Their presence causes false signals in mouse-antibody-based diagnostic immunoassays and can neutralize therapeutic efficacy, making reliable measurement essential for pre-treatment screening, immunogenicity monitoring during clinical trials, and troubleshooting anomalous diagnostic results.

Supplied by Assay Genie as a 96 Assays kit, the assay is built on a solid-phase immunoassay platform with chromogenic substrate readout and supports in vitro research workflows in pharmaceutical development and academic immunology laboratories. The package includes a pre-coated microplate along with calibrated standards and reagents for standard curve generation. Researchers process serum or plasma specimens obtained from individuals receiving mouse-derived biologics, with results supporting pharmacokinetic studies and patient stratification efforts. Store components refrigerated upon receipt and avoid repeated freeze-thaw cycles of working diluents to preserve reagent activity. For research use only, not intended for diagnostic procedures.