Human H2AFY2 ELISA Kit (HUFI03988)

MacroH2A2, encoded by the H2AFY2 gene, is a variant of histone H2A distinguished by a large C-terminal macro domain that influences nucleosome stability and gene silencing. This Assay Genie ELISA kit supports quantitative measurement of the human macroH2A2 protein in laboratory specimens, providing a tool for research into chromatin biology, X-chromosome inactivation, and epigenetic regulation. Reduced macroH2A2 expression has been reported in non-small cell lung cancer, melanoma, and breast cancer, where it can act as a tumor suppressor; the kit therefore fits oncology studies exploring histone variant balance as a biomarker or mechanistic readout. The colorimetric assay is configured for standard microplate workflows and supplied as a complete research-use-only kit with pre-coated wells, detection antibodies, calibrators, and buffer reagents, allowing laboratories to compare macroH2A2 levels across treated and untreated cell preparations.