Human H2AFX (Histone H2AX) ELISA Kit (HUFI05171)

The Assay Genie H2AFX (Histone H2AX) ELISA Kit supports quantitative detection of histone H2AX in human research specimens, advancing studies of DNA damage response and chromatin remodeling. H2AX is a key variant histone that becomes phosphorylated at serine 139 following DNA double-strand breaks, generating γH2AX foci that recruit repair factors to sites of genomic injury. This microplate-format kit uses paired antibodies with chromogenic signal development, allowing it to be incorporated into in vitro research workflows in radiation biology, genotoxicity testing, and oncological investigations. The kit aids researchers examining how nucleosome modifications contribute to genomic stability, apoptosis pathways, and cellular stress responses. Scientists studying DNA repair deficiencies, tumor suppressor mechanisms, or the chromatin-level effects of chemotherapeutic agents can apply this kit to monitor H2AX abundance across experimental cohorts. Supplied as a ready-to-use kit with all reagents required for the assay, it is intended for research use only and provides a reproducible tool for protein quantification in molecular and cell biology laboratories.