Human GZMK/Granzyme K ELISA Kit

From Assay Genie, this Sandwich ELISA kit is designed for the quantitative measurement of human Granzyme K (GZMK) in biological samples using a colorimetric double-antibody detection format. Granzyme K is a serine protease released by cytotoxic T lymphocytes and natural killer cells, contributing to apoptosis induction in target cells and implicated in various immune response processes.

The assay accepts serum, plasma, cell culture supernatant, cell or tissue lysates, and other liquid samples. Reported performance specifications include a sensitivity of 18.75 pg/mL and a measuring range of 31.25–2000 pg/mL. The kit is intended for research applications in immunology, oncology, and inflammatory diseases, where measurement of GZMK may support studies of immune system function, inflammatory responses, and potential therapeutic targets for immune-related disorders. Components should be stored at 2–8°C for up to 12 months.

Synonyms associated with the target include GZMK, NK-tryptase-2, NK-Tryp-2, Fragmentin-3, and Granzyme-3, with UniProt reference P49863, and the kit is listed under the cell biology research area. Reported linearity spans 86–105% for serum, 83–101% for EDTA plasma, and 81–100% for heparin plasma across serial dilutions. Average recovery values are 97% for serum, 96% for EDTA plasma, and 96% for heparin plasma.