Human GUCY1A3 ELISA Kit (HUFI04010)

The soluble guanylyl cyclase subunit alpha-3 (GUCY1A3) is a key mediator of nitric oxide (NO) signaling, converting GTP to the second messenger cyclic GMP upon NO binding. Quantification of this subunit in human-derived samples supports research into vascular biology, NO-cGMP pathway activity, and conditions associated with GUCY1A3 sequence variation, including primary achalasia and moyamoya-like cerebrovascular disease. The Assay Genie kit provides a microplate-based immunoassay for measuring GUCY1A3, intended for laboratory research use only. Researchers in cardiovascular pharmacology, smooth muscle physiology, and NO signaling typically pair this measurement with downstream cGMP assays, immunohistochemistry on vascular tissue, and cell culture models to investigate pathway activation. Reagents are shipped refrigerated and should be stored at refrigerated temperatures prior to use, with repeated freeze-thaw cycles avoided. Each kit includes antibody-coated wells, standard diluent, and detection reagents in individual vials for a single-use workflow.