Human Growth Differentiation Factor 5 (GDF5) ELISA Kit

This research-use immunoassay kit from Assay Genie is built to quantify Growth Differentiation Factor 5 (GDF5) in human specimens. GDF5, also called BMP-14, belongs to the TGF-β superfamily of signaling molecules and plays a central role in chondrogenesis, joint morphogenesis, tendon and bone repair, and limb skeletal patterning. Loss-of-function variants in the GDF5 gene are linked to brachydactyly type C, multiple synostoses syndrome, and other skeletal dysplasias, making the protein a frequent target in developmental biology, orthopedics, and regenerative medicine research.

The kit accommodates up to 96 assays per plate, supporting mid-throughput study designs in academic and translational laboratories. Compatible sample inputs include tissue homogenates, cell lysates, cell culture supernatants, and serum or plasma samples, allowing investigators to profile GDF5 expression across in vitro and in vivo model systems as well as clinical material. Researchers studying osteoarthritis progression, fracture healing, cartilage tissue engineering, and growth plate biology will find this reagent useful for measuring secreted and intracellular GDF5 levels in controlled experiments.