Human GPR50 ELISA Kit (HUFI04047)

Targeting GPR50, an X-linked orphan G protein-coupled receptor most abundantly expressed in the hypothalamus, pituitary, and hippocampal formation, this Assay Genie immunoassay provides a quantitative read-out of receptor protein in clinical research specimens. GPR50 heterodimerizes with MT1 and MT2 melatonin receptors and has been implicated in bipolar affective disorder, major depression, and metabolic traits through genome-wide association studies.

Investigators in circadian biology, neuropsychiatric disease, and energy homeostasis research can apply the kit to compare patient cohorts and matched controls. The microplate format supports batch processing, and the kit is shipped frozen on dry ice with components intended for single use aliquots to minimize freeze-thaw cycles of the standards and detection antibody. Incubations are performed at room temperature and absorbance is recorded with a standard plate reader after the addition of a stop solution, allowing integration into routine ELISA workflows.