Human GPR161 ELISA Kit (HUFI07844)

The orphan G protein-coupled receptor GPR161 localizes to the primary cilium and serves as a negative regulator of the Hedgehog signaling pathway during vertebrate development. Quantification of circulating GPR161 supports research into ciliopathies, neural tube defects, Joubert syndrome, and the receptor's emerging role as a tumor suppressor in certain cancers. This Assay Genie kit provides reagents for measuring GPR161 levels in vitro, offering researchers a tool to investigate Hedgehog pathway dysregulation, ciliary trafficking, and receptor dynamics in cell culture models and clinical research samples. The microplate format suits laboratory research use only workflows including biomarker discovery, signaling pathway analysis, and characterization of ciliary GPCR function in human specimens.