Human GNG2 (Guanine nucleotide-binding protein G (I)/G (S)/G (O)subunit gamma-2) ELISA Kit (HUFI04081)

GNG2 encodes the gamma-2 subunit of heterotrimeric guanine nucleotide-binding proteins (G proteins), molecular switches that operate at the interface between activated G protein-coupled receptors (GPCRs) and downstream effectors such as adenylyl cyclase, phospholipase C, and ion channels. This Assay Genie ELISA kit provides a quantitative immunoassay for measuring GNG2 protein levels in human-derived specimens, supporting research into cell signaling, receptor pharmacology, and membrane biology.

Configured in a microplate format and intended for research use only, the kit serves in vitro laboratory workflows. Reagents should be refrigerated upon arrival and equilibrated to ambient temperature before running the assay. Each kit supplies enough material for 96 individual determinations, accommodating medium-throughput studies of G protein pathway components.

GNG2 is broadly expressed across human tissues and has attracted interest in studies of receptor coupling specificity, neuronal signal transduction, and oncology, where altered expression of specific G protein subunits can reshape downstream responses. By targeting this particular gamma isoform, the assay allows researchers to resolve changes in GNG2 abundance separately from related subunits such as GNG3, GNG4, GNG5, and GNG7, which frequently co-localize within the same receptor complexes.