Human GNB4 ELISA Kit (HUFI04079)

Quantitative immunoassay for measuring G Protein Subunit Beta 4 (GNB4) in human biological samples. GNB4 encodes the beta subunit of heterotrimeric G proteins, which transduce signals from G-protein-coupled receptors to downstream effectors and influence neuronal signaling, ion channel modulation, and intracellular calcium handling. Mutations in GNB4 are clinically linked to Charcot-Marie-Tooth disease type 1D, making the protein a relevant target for neuroscience and hereditary neuropathy research.

This Assay Genie kit supports studies of GPCR signal transduction, beta-gamma subunit biology, and disease-associated variants. The plate-based protocol provides an absorbance readout, with reagents supplied in microplate format for laboratory throughput. Reconstituted standards and samples should be handled as aliquots to limit freeze-thaw cycles, and the kit is intended for research use only. Apply the assay to human serum or plasma specimens, cell culture supernatants, and tissue lysate preparations to investigate GNB4 expression under baseline and perturbed conditions.