Human GNAT1 ELISA Kit (HUFI04091)

The Assay Genie human GNAT1 ELISA kit enables quantitative measurement of G protein subunit alpha transducin 1 (GNAT1) in human research specimens. GNAT1 encodes the alpha subunit of transducin, a heterotrimeric G-protein that mediates the phototransduction cascade in retinal rod photoreceptors. The kit supports investigations into inherited retinal disorders, particularly autosomal dominant and autosomal recessive congenital stationary night blindness, where mutations in GNAT1 disrupt rod cell signaling and dark adaptation.

This research use only kit is supplied in a microplate configuration with reagents for an absorbance-based detection workflow. Applications extend to retinal cell signaling studies, G-protein coupled receptor pharmacology, photoreceptor biology, and ophthalmic disease model characterization. Researchers process human-derived liquid specimens under standard ELISA protocols, using the supplied reagents to quantify GNAT1 levels across patient cohorts, cell culture models, and tissue expression studies. The kit provides reagents for 96 individual determinations per plate, supporting high-throughput screening of clinical and experimental samples.