Human GNA14 ELISA Kit (HUFI07860)

GNA14 (Guanine Nucleotide-Binding Protein Alpha-14) is a heterotrimeric G protein alpha subunit belonging to the Gq/11 family, where it transduces signals from cell surface receptors to phospholipase C-beta and triggers intracellular calcium release. The Assay Genie kit is supplied as a complete kit containing a pre-coated microplate and all reagents needed to quantify endogenous GNA14 levels in human serum or plasma samples, with detection specific to the human GNA14 isoform, supporting studies of GPCR signaling, vascular smooth muscle regulation, melanocyte biology, and oncogenic research where activating GNA14 mutations have been documented in uveal melanoma and hepatic hemangiomas. Each plate includes reference standards for generating a standard curve, and the assay uses an enzyme-based detection readout. For optimal reagent activity, aliquot reagents upon receipt and store at 4 degrees C; consult the enclosed protocol for the recommended number of freeze-thaw cycles. For research use only.