Human GMDS ELISA Kit (HUFI04105)

The Assay Genie Human GMDS ELISA Kit provides researchers with a quantitative immunoassay for measuring GDP-mannose 4,6-dehydratase (GMDS) in human research samples. GMDS is the cytosolic enzyme responsible for the first committed step in the de novo biosynthesis of GDP-L-fucose, a nucleotide-sugar donor required for proper protein fucosylation, including the assembly of selectin ligands, Notch receptors, and ABO blood group antigens.

Researchers in glycobiology, cancer biology, and developmental biology use this kit to examine GMDS expression levels in human research samples. Published work has linked reduced GMDS activity to congenital disorders of glycosylation and to altered cellular fucosylation observed in certain tumor types, making this kit a useful tool for studies on fucose metabolism, glycosylation-related disease mechanisms, and biomarker discovery.

Assay Genie supplies the assay as a complete kit containing pre-coated microplate wells, detection reagents, and reference standards. The immunoassay procedure follows a standard microplate workflow that is compatible with conventional laboratory plate readers, and the kit format supports 96 individual sample determinations per run.