Human GM2A ELISA Kit (HUFI04103)

Targeting the GM2 activator protein (GM2A), a small lysosomal glycoprotein that serves as an essential cofactor for β-hexosaminidase A in the hydrolysis of GM2 ganglioside, this ELISA kit from Assay Genie supports quantitative measurement in human research samples. Because GM2A is indispensable for neuronal membrane lipid catabolism, loss-of-function mutations cause the AB-variant of GM2 gangliosidosis, a lysosomal storage disorder with neurodegenerative features resembling Tay-Sachs disease. Investigators working on ganglioside metabolism, lysosomal disease mechanisms, and candidate biomarkers in neurodegeneration rely on this assay to monitor GM2A expression in patient-derived and control specimens. Each kit supplies a pre-coated microplate, calibration standards, detection antibody, and substrate reagents for the immunoassay workflow, with readout on a standard plate reader. Reagents should be kept refrigerated and protected from light until use to preserve stability. Supplied as a complete research-use-only kit; not validated for diagnostic decision-making.