Human GM2 Ganglioside Activator (GM2A) ELISA Kit

GM2A is a small lysosomal glycoprotein (~22 kDa) that acts as an essential cofactor for β-hexosaminidase A, enabling catabolism of GM2 ganglioside in neuronal lysosomes. Loss-of-function mutations cause the AB variant of GM2 gangliosidosis, a Tay-Sachs–like neurodegenerative lysosomal storage disorder. Quantifying GM2A in human biofluids and tissue-derived extracts using this Assay Genie kit supports research into sphingolipid metabolism, neurodegeneration pathways, and inherited lipid storage diseases. Validated for in vitro research use only, store the microplate and reagents refrigerated to preserve antibody activity across repeated freeze-thaw cycles.