Human Glypican 3 PharmaGenie ELISA Kit (SBRS0646)

Assay Genie's Glypican-3 (GPC3) enzyme-linked immunosorbent assay quantitatively measures this cell-surface heparan sulfate proteoglycan in laboratory research samples. Glypican-3 is widely studied as a tissue marker associated with hepatocellular carcinoma (HCC), where it is highly expressed in malignant hepatocytes and fetal liver tissue, with minimal expression in healthy adult liver. Researchers apply this assay to investigate GPC3 expression patterns in cell culture models, xenograft studies, and patient-derived samples relevant to liver cancer research, tumor biology, and developmental biology.

The kit supports studies of the Wnt/β-catenin signaling pathway, where GPC3 modulates growth factor activity, as well as investigations into tumor cell proliferation, migration, and invasion. Common applications include screening for HCC biomarkers, validating GPC3-targeted therapies, and characterizing glypican expression in cell lines and primary tissue samples. The assay is supplied as a complete kit and is for in vitro research use only, intended for laboratory professionals conducting investigations in oncology and hepatology research.