Human Glycoprotein V, Platelet (GP5) ELISA Kit

Quantitative measurement of platelet Glycoprotein V (GP5) in human plasma is supported by this Assay Genie ELISA Kit, with applications in studies of platelet activation, thrombus formation, and Bernard-Soulier syndrome, a rare bleeding disorder rooted in defects of the GPIb-V-IX receptor complex that includes GP5. The 82 kDa protein contributes to the platelet adhesion apparatus that engages von Willebrand factor during primary hemostasis, and its circulating levels can serve as a biomarker in coagulation and cardiovascular research. Plasma is applied to a microplate pre-coated with anti-GP5 capture antibody, and bound analyte is revealed through an enzyme-substrate reaction read by absorbance. Kit components should be kept refrigerated to preserve antibody activity, with reconstituted standards and working solutions protected from repeated freeze-thaw cycles. The format supports the 96-assay workflow common in plasma biomarker work and is for research use only, including cohort screening, mechanistic investigation of GPIb-V-IX signaling, and correlation of GP5 levels with clinical phenotypes in platelet-related disease.