Human Glycine N-methyltransferase/GNMT ELISA Kit

This Sandwich ELISA from Assay Genie uses colorimetric detection and is designed for the accurate measurement of Glycine N-methyltransferase (GNMT) levels in human samples. The assay employs a Double Antibody format, offering high sensitivity and specificity for reproducible results across a variety of research applications. Validated linearity and recovery performance have been demonstrated in serum, EDTA plasma, and heparin plasma.

GNMT is an important enzyme involved in glycine metabolism and has been linked to diseases such as liver cancer, non-alcoholic fatty liver disease, and metabolic disorders. Measuring GNMT levels can provide insights into the enzyme's role in disease progression and help identify potential therapeutic targets. The kit delivers a sensitivity of 0.188 ng/mL with an assay range of 0.313–20 ng/mL.

Compatible sample types include serum, plasma, cell culture supernatant, cell or tissue lysate, and other liquid samples. Components supplied are a dismountable ELISA microplate, lyophilized standard, biotin-labeled antibody, HRP-Streptavidin conjugate (SABC), TMB substrate, sample dilution buffer, antibody dilution buffer, SABC dilution buffer, stop solution, wash buffer, plate sealer, and a technical manual. Storage is at 2–8°C for 12 months. The associated Uniprot reference is Q14749 and the research area is cell biology.