Human Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A) ELISA Kit

The Assay Genie GRIN2A ELISA Kit enables quantitative measurement of the GluN2A subunit of the NMDA receptor in human research samples. GRIN2A encodes the ionotropic glutamate receptor subunit that forms functional N-methyl-D-aspartate (NMDA) channels, which mediate calcium influx and downstream signaling critical to synaptic plasticity, excitatory neurotransmission, and neurological development. Researchers studying epilepsy-associated channelopathies, neurodevelopmental disorders, and excitotoxic injury use this kit to evaluate receptor subunit levels in tissue homogenates and cell lysates.

Each kit provides sufficient reagents for 96 assays in a single-use well plate format. The procedure uses a sequential incubation and wash workflow with an enzyme-conjugated detection reagent and a chromogenic substrate that produces a measurable signal proportional to GRIN2A concentration. All components arrive in labeled vials and should be stored refrigerated at the temperature specified in the package insert until first use.

Applications include investigation of NMDA receptor subunit expression in postmortem brain tissue, characterization of neuronal cell models under disease-relevant conditions, and screening of pharmacological compounds that modulate glutamatergic signaling. The product is intended for research use only and is not validated for diagnostic or clinical specimen testing.