Human Glutamate Dehydrogenase 1 (GDH) ELISA Kit

The Glutamate Dehydrogenase 1 (GDH) enzyme localizes to the mitochondrial matrix and catalyzes the reversible oxidative deamination of L-glutamate to alpha-ketoglutarate and ammonia, linking hepatic carbon and nitrogen metabolism. This Assay Genie kit supports quantitative measurement of GDH in research samples, with reactivity characterized against human, mouse, and rat GDH isoforms, enabling studies of urea cycle function, liver pathology, and the GLUD1 gain-of-function mutations underlying hyperinsulinism-hyperammonemia syndrome. Applications include investigation of neuronal glutamate recycling, pancreatic beta-cell insulin secretion regulation, and biomarker discovery in metabolic disease research. Unopened components should be stored at 4 degrees C in a refrigerated environment, with a shelf life sufficient for extended experimental planning. The kit is supplied in a microplate format compatible with standard laboratory plate readers.