Human Glutamate Decarboxylase 1, Brain (GAD1) ELISA Kit

Quantitative measurement of human GAD1 (glutamate decarboxylase 1, the 67 kDa brain isoform also called GAD67) is supported by this in vitro ELISA Kit from Assay Genie. The kit is supplied in a microplate-based format configured for ninety-six individual determinations and is intended for research use only, supporting studies in neuroscience, neuropharmacology, and autoimmune biomarker discovery where GABAergic signaling and inhibitory neurotransmission are of interest. The assay accepts tissue homogenates and cell lysates prepared from cultured human cell lines and neural tissue samples, enabling quantification of endogenous GAD1 protein expression. Detection relies on an enzyme-linked absorbance readout, with standards and detection reagents provided for generating a standard curve across the working dynamic range. Unopened components should be refrigerated to preserve reagent activity, in line with standard immunoassay storage practice; consult the supplied manual for component-specific handling and stability information. Applications include investigations of epilepsy, schizophrenia, autism spectrum disorder, stiff person syndrome, and type 1 diabetes mellitus, where altered GAD1 expression or anti-GAD autoantibody titers have been associated with disease mechanisms.