Human GLS2 (Glutaminase liver isoform, mitochondrial) ELISA KIT (HUFI08172)

GLS2 is a liver-type mitochondrial glutaminase encoded on human chromosome 12. The enzyme hydrolyzes glutamine into glutamate and free ammonia within the hepatocyte matrix, supporting ammonia detoxification through the urea cycle and contributing to gluconeogenesis. GLS2 has been characterized as a p53-responsive tumor suppressor with relevance to hepatocellular carcinoma research and non-alcoholic fatty liver disease studies.

Assay Genie's microplate-based immunoassay enables quantitative measurement of human GLS2 in research samples, supporting studies in hepatic metabolism, oncology biomarker discovery, and amino acid catabolism. Components include a pre-coated plate, biotinylated detection reagent, and substrate; refrigerate upon arrival and protect from light. Reconstituted standards should be aliquoted and stored frozen, with limited freeze-thaw exposure, to preserve immunoreactivity across multiple experiments.