Human GLRA1 ELISA Kit (HUFI04093)

The Assay Genie Human GLRA1 ELISA Kit quantifies Glycine Receptor Alpha 1, a ligand-gated chloride channel subunit that mediates inhibitory neurotransmission in the central nervous system, with prominent expression in the spinal cord and brainstem. Researchers use this microplate-based immunoassay to study glycinergic signaling, startle disease (hyperekplexia) caused by GLRA1 mutations, and altered receptor expression in neurodevelopmental and neuropsychiatric research contexts. Unopened kit components should be refrigerated; reconstituted standards and diluted detection antibody are best stored frozen at -20 °C in single-use aliquots to limit freeze-thaw cycles. Reconstituted standard stock is typically prepared at 1000 ng/mL before serial dilution along the standard curve. Each kit includes a pre-coated well plate, biotinylated detection antibody, streptavidin-HRP conjugate, wash concentrate, TMB substrate, stop solution, and lyophilized recombinant standard for use in ELISA workflows.