Human GFR alpha-1/GDNF R PharmaGenie ELISA Kit (SBRS0627)

Quantify glial cell line-derived neurotrophic factor receptor alpha-1 in human specimens using this Assay Genie immunoassay kit, which serves neuroscience, nephrology, and developmental biology research programs. The reagent targets GFR alpha-1, a GPI-anchored binding partner for GDNF that mediates downstream RET receptor activation and supports survival of dopaminergic neurons, enteric neurons, and renal ureteric bud branching.

Plasma, serum, and cell culture supernatant samples can be processed across a 96-assay microplate configuration with a colorimetric readout, making the workflow accessible to laboratories equipped with standard plate-reader instrumentation. Pre-coated wells, lyophilized standards, biotinylated detection antibody, streptavidin-HRP conjugate, wash buffer, substrate solution, and stop reagent are included to complete the full protocol.

Researchers investigating Hirschsprung disease mechanisms, Parkinson's disease models, spinal cord injury recovery, or spermatogonial stem cell self-renewal can deploy this kit to characterize receptor expression dynamics. The assay is calibrated exclusively for human reactivity and is labeled for research use only, supporting translational studies of neurotrophic pathway modulation.