Human GEF-H1 ELISA Kit (HUFI07868)

Researchers investigating Rho GTPase signaling, cytoskeletal remodeling, cytokinesis, and tumor invasion pathways can use this Assay Genie ELISA Kit to measure GEF-H1 protein concentrations in experimental samples. GEF-H1, also known as ARHGEF2, is a microtubule-associated guanine nucleotide exchange factor for RhoA that regulates mitotic spindle assembly, microtubule dynamics, and cell migration. Aberrant GEF-H1 expression has been documented in hepatocellular carcinoma, breast cancer, and other malignancies, making quantitative measurement valuable for oncology, signal transduction, and cell biology studies.

The kit includes all reagents required for the immunoassay procedure, supplied in a microplate format for research use only. Detailed protocols cover sample preparation, incubation steps, and absorbance reading, supporting reproducible data generation across runs. Applications include evaluating GEF-H1 responses to gene knockdown, small-molecule inhibitors, cytokines, or cellular stress conditions, and tracking expression changes in disease models, primary cell cultures, and treated tumor lines.