Human GDF-15 PharmaGenie ELISA Kit (SBRS0622)

For research laboratories investigating growth differentiation factor 15 (GDF-15), a stress-responsive cytokine of the transforming growth factor-beta superfamily also known as MIC-1, NAG-1, or PTGFB, the Assay Genie human GDF-15 PharmaGenie ELISA provides quantitative in vitro measurement. GDF-15 circulates as a disulfide-linked homodimer of approximately 25 kDa per monomer and is widely studied as a biomarker of mitochondrial dysfunction, cellular stress, and systemic inflammation. This 96-assay research-use-only kit delivers a colorimetric readout suitable for measuring endogenous human GDF-15 across cell culture supernatant samples and blood-derived specimens including plasma or serum. The assay supports diverse research programs: cardiovascular studies of heart failure prognosis, acute coronary syndrome risk stratification, and myocardial stress; oncology research into cancer cachexia, tumor progression, and chemotherapy response; metabolic investigations of obesity, type 2 diabetes, and non-alcoholic fatty liver disease; nephrology; and geroscience, where elevated circulating GDF-15 correlates with disease severity and all-cause mortality. Kit components include a pre-coated microplate, calibrated reference standards, biotinylated detection reagent, streptavidin-HRP conjugate, wash buffer, substrate, and stop solution. Investigators use the kit to track GDF-15 dynamics in response to pharmacological intervention, exercise, dietary modulation, or genetic manipulation in cell-based and translational studies.