Human GCDH (Glutaryl-CoA dehydrogenase, mitochondrial) ELISA KIT (HUFI05205)

The Assay Genie human GCDH ELISA kit enables quantitative measurement of glutaryl-CoA dehydrogenase, the mitochondrial flavin adenine dinucleotide-dependent enzyme that catalyzes the oxidative decarboxylation of glutaryl-CoA during lysine, hydroxylysine, and tryptophan catabolism. Investigators working on inherited metabolic disease use this assay to probe enzyme abundance in patient-derived material, supporting research into glutaric aciduria type 1, an autosomal recessive disorder arising from loss-of-function variants in the GCDH gene on chromosome 19p13.13.

Built around matched antibody pairs specific for human antigen, the kit supports work on mitochondrial enzyme regulation, screening of suspected GA1 cases, and characterization of the broader lysine degradation pathway. Each pack contains pre-coated microplate wells and the reagents needed to complete a full plate of determinations, with protocols tailored to standard research laboratory workflows and refrigerated storage between uses. The assay fits general research use only applications in biochemistry, clinical biomarker discovery, and studies of organic acidemia pathophysiology.